diff -u -p --recursive a/pyfits-3.3/setup.cfg b/pyfits-3.3/setup.cfg
--- setup.cfg	2014-07-17 14:36:07.000000000 -0400
+++ setup.cfg	2015-07-05 19:25:45.313176685 -0400
@@ -35,101 +35,29 @@ scripts =
 	scripts/fitscheck
 	scripts/fitsdiff
 
-[extension=pyfits.compression]
-sources = 
-	cextern/cfitsio/adler32.c
-	cextern/cfitsio/buffers.c
-	cextern/cfitsio/cfileio.c
-	cextern/cfitsio/checksum.c
-	cextern/cfitsio/crc32.c
-	cextern/cfitsio/deflate.c
-	cextern/cfitsio/drvrfile.c
-	cextern/cfitsio/drvrgsiftp.c
-	cextern/cfitsio/drvrmem.c
-	cextern/cfitsio/drvrnet.c
-	cextern/cfitsio/drvrsmem.c
-	cextern/cfitsio/editcol.c
-	cextern/cfitsio/edithdu.c
-	cextern/cfitsio/eval_f.c
-	cextern/cfitsio/eval_l.c
-	cextern/cfitsio/eval_y.c
-	cextern/cfitsio/fitscore.c
-	cextern/cfitsio/fits_hcompress.c
-	cextern/cfitsio/fits_hdecompress.c
-	cextern/cfitsio/getcolb.c
-	cextern/cfitsio/getcol.c
-	cextern/cfitsio/getcold.c
-	cextern/cfitsio/getcole.c
-	cextern/cfitsio/getcoli.c
-	cextern/cfitsio/getcolj.c
-	cextern/cfitsio/getcolk.c
-	cextern/cfitsio/getcoll.c
-	cextern/cfitsio/getcolsb.c
-	cextern/cfitsio/getcols.c
-	cextern/cfitsio/getcolui.c
-	cextern/cfitsio/getcoluj.c
-	cextern/cfitsio/getcoluk.c
-	cextern/cfitsio/getkey.c
-	cextern/cfitsio/group.c
-	cextern/cfitsio/grparser.c
-	cextern/cfitsio/histo.c
-	cextern/cfitsio/imcompress.c
-	cextern/cfitsio/infback.c
-	cextern/cfitsio/inffast.c
-	cextern/cfitsio/inflate.c
-	cextern/cfitsio/inftrees.c
-	cextern/cfitsio/iraffits.c
-	cextern/cfitsio/modkey.c
-	cextern/cfitsio/pliocomp.c
-	cextern/cfitsio/putcolb.c
-	cextern/cfitsio/putcol.c
-	cextern/cfitsio/putcold.c
-	cextern/cfitsio/putcole.c
-	cextern/cfitsio/putcoli.c
-	cextern/cfitsio/putcolj.c
-	cextern/cfitsio/putcolk.c
-	cextern/cfitsio/putcoll.c
-	cextern/cfitsio/putcolsb.c
-	cextern/cfitsio/putcols.c
-	cextern/cfitsio/putcolu.c
-	cextern/cfitsio/putcolui.c
-	cextern/cfitsio/putcoluj.c
-	cextern/cfitsio/putcoluk.c
-	cextern/cfitsio/putkey.c
-	cextern/cfitsio/quantize.c
-	cextern/cfitsio/region.c
-	cextern/cfitsio/ricecomp.c
-	cextern/cfitsio/scalnull.c
-	cextern/cfitsio/swapproc.c
-	cextern/cfitsio/trees.c
-	cextern/cfitsio/uncompr.c
-	cextern/cfitsio/wcssub.c
-	cextern/cfitsio/wcsutil.c
-	cextern/cfitsio/zcompress.c
-	cextern/cfitsio/zuncompress.c
-	cextern/cfitsio/zutil.c
-	src/compressionmodule.c
-include_dirs = 
-	numpy
-	cextern/cfitsio
-extra_compile_args = 
-	-Wno-declaration-after-statement
-	-Wno-unused-variable
-	-Wno-parentheses
-	-Wno-uninitialized
-	-Wno-format
-	-Wno-strict-prototypes
-	-Wno-unused
-	-Wno-comments
-	-Wno-switch
-optional = True
-fail_message = 
-	!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
-	Failed to build PyFITS tile compression support.  PyFITS will still
-	function, but without the ability to read or write compressed images.
-	Please seek support from help@stsci.edu if you need this capability.
-	!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
-
+#[extension=pyfits.compression]
+#sources = 
+#	src/compressionmodule.c
+#include_dirs = 
+#	numpy
+#extra_compile_args = 
+#	-Wno-declaration-after-statement
+#	-Wno-unused-variable
+#	-Wno-parentheses
+#	-Wno-uninitialized
+#	-Wno-format
+#	-Wno-strict-prototypes
+#	-Wno-unused
+#	-Wno-comments
+#	-Wno-switch
+#optional = True
+#fail_message = 
+#	!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
+#	Failed to build PyFITS tile compression support.  PyFITS will still
+#	function, but without the ability to read or write compressed images.
+#	Please seek support from help@stsci.edu if you need this capability.
+#	!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
+#
 [global]
 setup-hooks = 
 	stsci.distutils.hooks.version_setup_hook
diff -u -p --recursive a/pyfits-3.3/setup.py b/pyfits-3.3/setup.py
--- setup.py	2014-06-09 16:07:11.000000000 -0400
+++ setup.py	2015-07-05 20:46:43.071332734 -0400
@@ -1,15 +1,41 @@
 #!/usr/bin/env python
 
 try:
-    from setuptools import setup
+    from setuptools import setup, Extension
 except ImportError:
     from ez_setup import use_setuptools
     use_setuptools()
-    from setuptools import setup
+    from setuptools import setup, Extension
 
+import sys
+import subprocess
+
+
+PY3 = sys.version_info[0] == 3
+extra_compile_args = ['-Wall']
+extra_link_args = ['-lcfitsio']
+
+try:
+    if PY3:
+        extra_compile_args = subprocess.check_output(['pkg-config', '--cflags', 'cfitsio']).decode().split()
+        extra_link_args = subprocess.check_output(['pkg-config', '--libs', 'cfitsio']).decode().split()
+    else:
+        extra_compile_args = subprocess.check_output(['pkg-config', '--cflags', 'cfitsio']).split()
+        extra_link_args = subprocess.check_output(['pkg-config', '--libs', 'cfitsio']).split()
+except subprocess.CalledProcessError:
+    print('!!! pkg-config failure, skipping flag generation !!!')
+    pass
 
 setup(
     setup_requires=['d2to1>=0.2.5', 'stsci.distutils>=0.3'],
     d2to1=True,
-    zip_safe=False
+    use_2to3=True,
+    zip_safe=False,
+    ext_modules = [
+        Extension('pyfits.compression', ['src/compressionmodule.c'],
+                  include_dirs=['numpy'],
+                  extra_compile_args=extra_compile_args,
+                  extra_link_args=extra_link_args,
+                  optional=True)
+        ],
 )